Sulfonylureas (SU) are group of substituted urea herbicides, primarily used for the control of weeds (annual and perennial) in early growth stages of cultivations. Structurally they consist a sulfonyl group (-S(=O)2) (Fig. 1). The side chains (R1 and R2) distinguish various sulfonylureas, such as pyrimidinyl-sulfonylureas and the triazinyl-sulfonylureas.
Figure 1. Structural formula of...
The development of industry and technology has led to the increasing water pollution, causing many hidden dangers to human health and lives. 1 Wastewater from the textile industry is classified as the most polluting of all industrial sectors in terms of effluent volume and chemical content. Advanced oxidation processes (AOPs), based on the generation of highly active species, such as hydroxyl...
Ibuprofen is a nonsteroidal anti-inflammatory drug with non-narcotic, analgetic and antipyretic action. It is widely used in the treatment of pain in many different pharmaceutical preparations. The usage of alcohols as excipients is known in topical preparations to increase the solubility of ibuprofen, as well as to enhance its skin permeability. Because of the chemical nature of ibuprofen,...
Dopamine (DA) is an important neurotransmitter for the function of the central nervous, renal, endocrine and cardiovascular systems. The development of a simple, selective and sensitive method to detect DA is necessary to monitor the level of DA in the human body. Many approaches have been developed for the detection of DA. The electrochemical analysis technique has received much attention as...
The investigation of the quantitative structure activity/property relationships (QSAR/QSPR) of organic compounds is an essential aspect of present experimental chemistry, biochemistry, medicinal chemistry, and especially in drug discovery. The obtained information is composed of mathematical equations relating the chemical structure of the compounds to a wide variety of their physical,...
In the last decade, the rapid and fast development of information exchange, online communication technologies (ICT) and also multimedia content has definitely improved and modernized the quality of education worldwide. The needs for changes in all levels of education experienced an expansion, especially in the beginning of global pandemic in 2020, after the confirmation of the presence of the...
The aim of this work was application of the kinetic-spectrophotometric method for the Co(II) ion determination in baby tea samples. Cobalt is an essential element and it is important for the function of many vital processes, such as the production of erythrocytes, i.e. red blood cells, as well as in the production of antibacterial and antiviral compounds that prevent the occurrence of...
Topic: Inorganic chemistry and technology,inorganic materials and metallurgy
Zeolites are three-dimensional crystalline compounds that are built from AlO4 and SiO4 tetrahedra. The tetrahedral structures of zeolites can be further linked into different rings. Such structures are called secondary building units. They can contain more than 16 atoms in the ring (only the atoms located in the...
Silymarin is a mixture of flavonolignans of the plant Silybum marianum (L.) Gaerth derives mainly from its fruits. S. marianum has been found to exhibit antioxidant, lipid-lowering, antihypertensive, antidiabetic, antiatherosclerotic, anti-obesity, and hepatoprotective effects. In modern therapy, standardized silymarin products are used. According to the European Pharmacopoeia (Ph.Eur.11.0),...
The need for constant improvements of wound dressing materials and advancement of their properties is an ever-present element of biomaterials science research. The biomaterials field is always evolving towards finding new wound dressing formulations which can provide active protection of the wound from bacterial infections, rather than just being a passive barrier for infiltration of bacteria....
Biologically active fibers as drug carriers have improved characteristics in comparison with conventional medical therapies. Cellulose as a hydrophilic and biocompatible, nontoxic and eco-friendly material, makes a good polymer matrix for obtaining biologically active fibers.
The aim of this study was to investigate the possibility of obtaining biologically active materials by sorption of...
Various types of pesticides are used to improve agricultural productivity and maintain the freshness of agricultural products. However, due to increasing and uncontrolled application, pesticides and their derivatives represent a major threat to entire ecosystems. Therefore, development of new methods for their detection and monitoring is of primary matter. In present work, the unmodified...
Rare-earth aluminates (LaAlO3 and GdAlO3) and their calcium-substituted derivates (La1-xCaxAlO3-δ; x = 0.05, 0.10, 0.15 and 0.20; Gd1-xCaxAlO3-δ; x = 0.05, 0.10 and 0.15) are prepared via one-step mechanochemical processing of simple oxide precursors at ambient temperature. In the case of mechanochemical formation of the GdAlO3, the reaction is accompanied by Gd2O3 phase transformation. The...
Calcium orthophosphates are of particular interest among the other phosphorus inorganic compounds because calcium orthophosphates are the mineral basis of the bone tissues. The latest requirements not to test new materials on living organisms pose a challenge to finding suitable artificial substitutes.
In this work, the possibility of using ceramic tablets based on hydroxyapatite (HA), which...
Over 90 million tons of textile waste is produced every year. A large share of waste comes from the goods made of cellulose fibers. Recently, special attention has been directed towards the use of textile cellulose waste for clean-up of oil spills1. The major problem relies on their relatively small oil capacity and complex separation of individual cellulose fibers from the treated spills. In...
The primary goal of this study was to characterize three pottery vessels excavated at the archaeological site Stobi. The significance of the study lies in the fact that it presents an initial publication of research conducted on these objects, encompassing multiple analytical aspects such as chronology, technology and experimental analysis.
Based on comprehensive investigations, the examined...
*tina.skalar@fkkt.uni-lj.si
Phase change materials (PCMs) have attracted considerable attention in the field of heat storage due to their ability to absorb and release large amounts of latent heat during phase transitions. The integration of PCMs into building materials offers promising opportunities for improving the thermal performance and energy efficiency of buildings.1
This paper...
The GC, GC-MS, and NMR techniques were utilized to examine the phytochemical composition of Microbiota decussata. A comparative analysis was performed with a previously published study conducted by Raldugin et al. in 1981.1 In contrast to the findings of the Russian group, our sample did not contain hedycaryol, which was identified as the major alcohol component. Instead, thujopsan-2α-ol...
Numerous millipede species produce a defensive secretion that contains a variety of volatile compounds grouped into alkaloids, quinones, phenols, and esters.1 Chemical composition of defensive secretion is unknown for the majority of members of the genus Pachyiulus Berlese, 1883 and up to now analyses of secretion constituents were done only for P. hungaricus and P. cattarensis.1,2...
Cleaning validation is documented evidence that an approved cleaning procedure will consistently remove previous product or other residues on product contact equipment surfaces below scientifically set acceptable levels. The cleaning validation consequently ensures that the quality of the next product manufactured shall not be compromised by cross-contamination.1,2
The aim of this study was...
The chemical composition of commercial marjoram (Origanum majorana) essential oils sourced from southeastern Serbia and Egypt was investigated using GC and GC-MS techniques. The major volatile compounds in both oils were terpinen-4-ol and γ-terpinene, constituting approximately 50% of the oils based on GC peak areas. However, there were significant differences between the two oils in terms of...
Emission of volatile organic compounds (VOCs) leads to a significant decrease in air quality in many regions around the world and has a negative impact on climate change, human health and the biosphere. Quantitative analysis of these substances by gas chromatography coupled to mass spectrometry (GC-MS) is especially challenging since VOCs are usually present in ambient air at low levels...
Gamma irradiation as a valuable technique enables structural modification such as introduction of desired functional groups and surface properties enhancement, expanding the potential applications of carbon nanomaterials in various fields. A study on gamma irradiation interaction with carbon nanostructures was conducted to investigate and unlock their full application potential. Three carbon...
Interpretations of observed solvent effects on light absorption and emission by dye molecules have traditionally been associated during recent decades with time dependent density functional theory.1 More sophisticated theoretical approaches have been applied to small molecular examples only. Here we compare some ways of accounting for the solvent effect using model specific solvent-solute...
During the COVID -19 pandemic circumstances, not only was the teaching process at universities suddenly converted to online teaching and learning, but examinations also had to be conducted online in most cases, although it was not always possible to ensure strict control. While it is still relatively easy to provide proper proctoring for individual oral exams, it is more difficult to do so for...
Recently, there has been an increasing interest in developing non-aqueous electrolytes which have been widely employed as an alternative media for a range of metals and metal alloys electrodepositions. A promising and new class of electrolytes among ionic liquids (ILs) are deep eutectic solvents (DESs)1. The purpose of the copper deposition study from DESs is the application of copper coating...
Tin dendrites found wide application in various industries.1 They can be obtained by both non-electrochemical and electrochemical methods of synthesis. In this study, they were produced by a galvanostatic regime of electrolysis from alkaline hydroxide solution at a current density of –3 mA cm–2, 1.5 times larger than the limiting diffusion current density, with an amount of the electricity of...
Hydrogen bond solvation affects molecular properties and functions both in solution and solid-state formation of solvates. Many of Active Pharmaceutical Ingredients (APIs) exist as solvates with different solvents that, depend on the nature and polarity, co-crystallize with their appropriate molecular structures in wide range of polarity, either non-ionizable or deprotonated acids and bases...
In the last decade, the most investigated perovskite materials are the hybrid organic-inorganic perovskites (HOIPs) due to their optoelectronic properties and possible application in production of photovoltaics. As a result, there is a continuous ongoing search for new ones, but also a thorough investigation of the properties of already known HOIPs. Here we present the cyclic voltammetry study...
Breast cancer is the most prevalent malignancy in women worldwide and is heterogeneous and highly complex in nature. Curcumin, owing to its pleiotropic molecular structure and recognized bioactivities, has established its role in anticancer research. Regarding curcumin’s limiting factors from therapeutic applicative aspect, the monocarbonyl analogs of curcumin (MACs), possessing improved...
This study prepared a modified cobalt oxide (Co3O4) carbon paste electrode to detect Levofloxacin (LEV). Co3O4 nanoparticles were synthesized by the chemical coprecipitation method. The electrochemical properties of LEV at this electrode were investigated by cyclic voltammetry (CV) and square wave voltammetry (SWV). In addition, electrochemical impedance spectroscopy (EIS), inductively coupled...
In order to achieve widespread application of fuel cell technology, the development of an efficient and economical catalyst is a crucial step. Reducing the diameter of catalyst particles, producing particles with a specific orientation surface, and alloying noble metals with less expensive metals are possible approaches to improve catalyst performance. This study will be focused on novel ways...
Organic emissions in outdoor urban air were monitored in selected cities in the Republic of N. Macedonia and Kosova in 2022 using Radiello® passive/diffusive samplers and gas chromatography coupled with mass spectrometry. Furthermore, BTEX compound ratios and correlations have been employed as a marker for finding VOC emission sources in the atmosphere.
Macroporous (glycidyl methacrylate) GMA-based composite was synthesized via suspension polymerization in the presence of 2 wt. % magnetic nanoparticles and functionalized with triethylenetetramine. Copper was immobilized on composite by contacting modified copolymer with 0.1 M solution of CuCl2, at pH 5, and 25 ̊C. The obtained composite was characterized by mercury porosimetry, Fourier...
Abstract: Pre-impregnated material is used for high performance composite parts where control of resin content and the greatest versatility of material placement is required. The two main methods used for producing thermosetting prepregs are hot-melt and solvent-based impregnations. In solvent-based prepreg processing, the most important processing parameters are the temperature in the...
Reduced graphene oxide/metal phthalocyanines (rGO/MPcs) are known for their outstanding optical properties. However, their synthesis is quite complicated and expensive with low material yields. Therefore, the aim of this research work was to investigate the option of placing this expensive material within polymer film and to study the optical properties of such polymer composites, in which low...
Healthy drinking water is a basic prerequisite for good health, as it is necessary for maintaining life and personal and general hygiene. The World Health Organization (WHO) classified the quality of drinking water into twelve basic indicators of the health status of a country's population. The quality of drinking water is a constant task for the employees of any water factory. Quality...
The analytical method is one of the deciding factors in establishing the cleanliness of pharmaceutical manufacturing equipment.1 The purpose of this research is to develop and validate sensitive and accurate HPLC method, suitable for quantitative determination of propyphenazone residues on manufacturing equipment.
The method has been validated to show specificity, linearity and range,...
In this work, high entropy oxides with MAl2O4 spinel structure, i.e. (Zn0.25Cu0.25Co0.25Mg0.25)Al2O4, were successfully synthesized via one-step mechanochemical method.Moreover, their lithiated derivates of the final composition: Li0.5(Zn0.125Cu0.125Co0.125Mg0.125)0.5Al2O3.5F0.5,Li0.5(Zn0.125Cu0.125Co0.125Mg0.125)0.5Al2O3.5Cl0.5 were prepared by mechanochemical reaction between oxide...
It is clear that humans consume more natural resources to meet all the needs of our growing population and modern lifestyle, but those resources being depleted at an alarming rate. Also, in order to enable continued progress and improve human life, it is necessary to develop new materials with improved properties. For this reason, researchers must invest a great deal of effort into finding...
The aim of this research was to determine effect of coffee roasting temperature in industrial conditions on: (i) the nutritive quality of coffee (Arabica 1st class, Arabica 2nd class, Robusta); (ii) sensory quality of traditionally prepared black coffee beverage; (iii) correlation between roasting temperature and beverages sensory quality. The basic chemical composition, titrable acidity, pH...
Orange-carbon dots (o-CDs) have the potential to enhance photosynthesis and productivity in plants playing an important role in agroindustry1. Therefore, it is of interest to estimate regarding possible oxidative stress they may initiate in plants. This study reports the impact of o-CDs on the parameters of secondary metabolism - total antioxidative activity (TAA) and total phenolic content...
Biotechnology and food technology (BFT)
Effect of pure anethole and synergistic interaction of anethole with different essential oils- potential alternative biocontrol products against plant pathogens.
Antimicrobial activities of tested fungi and their potential application might provide an alternative way to fight against plant fungal pathogens. If they can be considered safe for plants...
Cheese produced by thermal denaturation, followed by aggregation and precipitation of the whey proteins is known as whey cheese. Lactic acid bacteria are not included in the production, therefore, whey cheese does not require a ripening period. The whey cheese shelf-life is notably shorter compared to other cheese types due to the higher moisture quantity and high water activity value. Urda is...
BaTiO3 is a ceramic lead-free material which is extensively investigated due to its ferroelectricity and piezoelectricity, which opens a wide applications in many electronic devices such as capacitors and nanogenerators.1 In comparison with nanoparticles, the 1D nanostructured BaTiO3 such as wires, tubes and fibers have attracted substantial attention due to their high aspect ratio and unique...
In the last decades, self-heating magnetic nanoparticles (MNPs) were engineered and investigated for magnetic hyperthermia (MH) and other applications such as catalysis and chemical synthesis. To be applied as nanoheaters for in vivo MH in cancer therapy, MNPs should have high heating efficiency expressed by Intrinsic Loss Power (ILP). One of the requirements for in vivo applications of MNPs...
The objective of this study was to enhance the shelf life of strawberries using natural antimicrobial components applied to edible biofilms. To achieve this, a thin edible film composed of chitosan infused with essential oils from basil and clove was applied to the strawberries. Results showed that the coated strawberries exhibited a significant reduction in the number of infections compared...
The uncertainty in measurement is a crucial segment of the estimation of experimental analytical results. Moreover, the results without an uncertainty estimation cannot be considered as complete. The aim of this work was an estimation of the combined standard and extended measurement uncertainty (MU) for three simple and rapid methods for routine determination of total chlorides content in...
Anthocyanins are bioactive compounds that are present in various fruits and vegetables. They can enhance the visual appeal of food products, as they are responsible for their vibrant purple, blue and red hues. Anthocyanin-rich extracts obtained from plants can change colour in response to pH, temperature, light and oxygen variations. By changing their colour accordingly to the pH of the food...
An inductively coupled plasma atomic emission spectrometry (ICP AES) method for determination of 21 elements (Al, As, B, Ba, Ca, Cd, Cr, Co, Cu, Fe, K, Mg, Mn, Na, Ni, P, Pb, Si, Se, V and Zn) in Rosa dumalis Bechst samples was optimized and then validated. Robust plasma conditions were reached at an radiofrequency power of 1150 W and an argon nebulizer flow of 0.5 L min-1. All experiments in...
Electrospinning provides an attractive means of producing micro/nanoscale polymeric fibers because of its simplicity, reproducibility, and scale-up possibilities. Electrospun polymeric scaffolds mimic natural three-dimensional extracellular matrix (ECM), which is composed of complex fibrous structures with porous architectures, and thus, can be used to promote cell, tissue, and/or organ...
Tuff is a type of volcaniclastic rock formed by the deposition of finer volcaniclastic material. Zeolitic tuffs are rocks that contain zeolites as well as various other crystalline or amorphous phases. In the Piplići deposit located 5 km southeast of Prnjavor, the average thickness of the only tuff layer is about 10 m, and it is interstratified within a complex of gray clayey sandstones...
The constant K/S represents the relationship between the concentration of the color and its emission value, where K is the absorption constant for a certain wavelength and S is the vertical regulation constant also for a certain wavelength (only for the material, depending on the coloring of textiles, leather or paper). As early as 1931. Kubelka and Munk came to the following mathematical...
Nanostructured materials present unique properties as electrocatalysts for various industrial needs such as electrochemical energy conversion and storage.1 Aiming to enhance the electrocatalytic properties of Pd towards the electrochemical oxidation of ethanol, we used the electrodeposited Sn dendrites as a sub-layer for Pd. We tested the resulting Sn-Pd electrocatalysts for ethanol oxidation...
Producing safe food is a goal and an obligation for each producer. Mycotoxins by representing the most significant contaminants of grain are considered to be the main risk in the production of safe bakery products.1
Conditions during the production process defined by temperature regime, duration of the temperature regime, moisture content, pH value, as well as the type and level of...
Lactic acid bacteria (LAB) are employed as a biotechnological starters to improve the safety and functionality of food and feed, to provide added value and to increase safety of food industry by-products (to reduce mycotoxins, acrylamide, polycyclic hydrocarbons, etc., concentration), to design synthesis of functional molecules (e.g., vitamins, free amino acids, volatile compounds, fatty...
Quality of air in cabin of transportation vehicle is becoming even more important nowadays with increase in globalization and transportation . Vehicular combustion is the most substantial source of pollution in densely populated urban areas. It is constituted of gaseous pollutants and ultrafine particulate matter (UFP)) descibed as PM values. Intensive industrial development an fossil...
Water contamination is a serious problem and increase the concern because of its effects on living organisms as well as the surrounding environment. Microorganisms, organics, and inorganics are the three primary types of pollutants found in water. Because of their toxicity to ecological and biological processes, heavy metals ions (HMI), which make up the ma jority of inorganic contaminants,...
In this study, the formic acid electrooxidation reaction was studied on a platinum thin film catalyst obtained by deposition on chromium support (Pt/Cr). In an attempt to reduce the proneness of Pt to poisoning species i.e. CO and improve the catalytic performance of Pt/Cr at low potentials in the formic oxidation reaction, the as-prepared catalyst was modified using controlled thermal...
Frost resistance mechanisms and biocorrosion as major processes that leads to weathering of ceramics are of great practical and scientific interest upon their exposure to surrounding environmental conditions.
The aim of this work was to define the influence of different deterioration mechanisms regarding both frost and biocorrosion actions on ceramic composites in which a significant part of...
Natural deep eutectic solvent glyceline, constituted of choline chloride and glycerol in a 1:2 molar ratio, was tested for the purification of crude biodiesel. Low-acid value expired sunflower oil (0.61 mg KOH/g) was used as a feedstock for biodiesel production, prepared by the CaO-catalyzed oil methanolysis carried out at the methanol-to-oil molar ratio of 6:1, CaO amount 2.5% to oil,...
The main goal of this study was the evaluation of physical–chemical, as well as radiological properties of residual materials used for synthesis of alkali activated materials (AAMs) for the possible application as new materials in a civil engineering industry. Also, the purpose of this research is to investigate the hydrophobicity of new alumino-silicate materials and the influence of Si/Al...
Rare earth metals, mainly related to neodymium, praseodymium or dysprosium are usually produced by molten salt electrolysis in which oxy-fluoride or chloride molten salt systems are used as the electrolytic bath. Minimizing the perfluorocarbon compounds (PFC) emission in rare earth electrolysis should be the primary goal owing to their high global warming potential1. There is growing interest...
The drying process of film-forming formulations such as paints and coatings involves the assembly of micro and nanoparticles and aggregates in suspension into a film as the solvent evaporates. The ways in which these ingredients are assembled will dictate the architecture of the dried coating and therefore its performance. For example, in the case of antibacterial paint, the amount of...
Heterogeneity of adsorption and reaction sites of Со-Pd/SiO2 catalysts for CO hydrogenation was studied by chemisorption, TPD, and DRIFTS. Precursor materials were treated in H2, Ar, or air and named respectively as (red), (inert), or (ox). CO conversion changed in low extent due to effect of preliminary treatment. Activity of samples in synthesis of CH4 ranged as (inert)<(ox)<(red) and...
In much of educational research, organic chemistry is considered as one of the more difficult areas of chemistry. It is due to the amount of content to be taught, but mostly to its complexity, and consequently to the misconceptions in the basic concepts that might arise. Among the most difficult topics in organic chemistry are those concerning the concepts of stereochemistry, such as...
In the last decade, the global changes in life style and increased health awareness of the consumers, put pressure on producers to develope or more accurately re-designed food products with reduced glycaemic index, lower salt content, lower fat content, lactose free etc to sustain the consumer acceptability. These requirements need a broad knowledge not only of the chemical part and content of...
Abstract
The present research was conducted in order to evaluate possibility of implementation of new methodology of testing of body cooling systems into the education process at Military Academy in Belgrade. According to previous evaluation of personal body cooling systems based on different technologies and its effects on human's physiological suitability during exertional heat stress in...
Lycopene, a potent antioxidant associated with remarkable health benefits, found in high concentrations in tomato skins, holds immense importance when extracted from waste materials. Utilizing tomato skins as a source of lycopene offers several benefits. Firstly, it helps reduce food waste and supports sustainable practices by utilizing a byproduct that would otherwise be discarded. Improving...
The aim of the work is to improve an advanced consolidation system for cultural heritage materials in order to accelerate the carbonation of the consolidation process. The research represents a step towards a circular economy, as it is expected to increase the sustainability of the historical material thus consolidated and to improve the carbonation of the consolidation process, which will...
The key ability of cyclodextrins to form inclusion host-guest complexes found numerous applications in pharmacy, medicine, food, textile, and cosmetic industry, agriculture, nanotechnology, and other fields.1 Regarding this, in this work, the synthesis of β-cyclodextrin inclusion complexes with protocatechuic and vanillic acid derivatives (esters, hydrazides, and pyrazoles) was performed in...
The purpose of this work was to study the effect of used (polyether, polyester and polycarbonate) soft segment on structure, morphology, crystallinity and some physicochemical, thermal as well as antibacterial activity of new type TPUs. These polymers were synthesized from poly(oxytetramethylene) diols (PTMO)s of = 1000Da and = 2000Da, poly(ε-caprolactone) diol (PCL) of = 2000Da and...
Due to the numerous chemicals in daily use, there are many compounds that reach the environment unintentionally and/or uncontrolled, which presence is not subjected to regular monitoring or control measures. Hence, there are many different classes of these so-called compounds of emerging concern (CECs) such as pharmaceutically active compounds, personal care products, polar pesticides, poly-...
Nowadays, the use of renewable biobased carbon feedstock from different resources, such as vegetable oils, is highly taken into consideration because it offers the intrinsic value of a reduced carbon footprint with an improved life cycle analysis, in agreement with a sustainable development. Besides, compared to conventional fossil-based materials, innovative macromolecular architectures with...
Examination and understanding of interactions between active pharmaceutical ingredients (APIs) and other constituents of solid dosage forms, including lubricants, is one of the crucial steps in pharmaceutical formulation and manufacturing process. Lubricants are additives used in small quantities whose role is to reduce friction between the contact surface of the manufacturing equipment and...
This research aims to solve several problems in the environment imposed on us by modern society. The first is the removal of the systematic insecticide imidacloprid from the group of neonicotinoids, whose mass use in agriculture leads to elevated concentrations in water, which manifests negative effects on the environment1. Also, huge amounts of waste products in the form of fly ash and boiler...
To fully exploit the therapeutic potential of curcumin, overcoming its pharmacokinetic limitations is crucial. An effective strategy for addressing this challenge involves replacing the central 1,3-diketo moiety of curcumin with a single carbonyl group. Inspired by this promising approach, we synthesized a series of monocarbonyl analogs of curcumin (MACs).
The objective of this study was to...
Nanometric size Co0.9Ho0.1MoO4 powder particles were obtained by applying glycine nitrate procedure (GNP). Powder properties have been studied by DTA, X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectra, Spectroscopy, Field emission scanning electron microscopy (FESEM), and nitrogen adsorption method. The photocatalytic activity of acquiring Co0.9Ho0.1MoO4 nanopowders was...
The aim of this work was the synthesis and characterization of new poly(thiourethane-urethanes) containing siloxane groups in their structure. The aliphatic diisocyanate, i.e. 4,4'-dicyclohexylmethane diisocyanate (HMDI), was used as raw materials, the soft segment was poly(-caprolactone) diol (PCL), while the chain extender was (methanediyl-dibenzene-1,4-diyl)dimethanethiol (DMT),...
The IR-ATR and IR transmittance spectra of(4-O-acetyl ferula-to)triphenyltin(IV) and (fenoprofenato)tributyltin(IV)1 were recorded and analyzed. It was possible using the splitting of the (COO) band in the IR spectrum of the com-pounds to prove amonodentate binding mode of the carboxylate group to the Sn at-om. Also, the IR-ATR spectrum of theMCM-41 and SBA-15 mesoporous silica nano-particles...
Significant amounts of unused and discarded wool from domestic sheep in BiH represent waste and unused of this significant natural fibre. Keratin, which is an integral part of wool, is a renewable biopolymer with biocompatibility and biodegradability properties. Due to the content of a large number of functional groups, regenerated keratin can be used to make highly absorbent nanofibers for...
Dyes are comprehensively used in food, textile, plastic, metal, pharmaceutical and many other industries. Currently, more than 700 000 tons of dyes are required each year, of which at least 10–15% are discarded into the wastewater and responsible for water pollution. These dyes alter the color of water, and inhibit light penetration, reducing the rate of photosynthesis and the oxygen level,...
Hexavalent chromium, Cr(VI), is one of the most notorious pollutants with health and environmental impacts due to carcinogenic, teratogenic, and mutagenic effects on the human organism.1 Therefore, treating wastewater containing Cr(VI) before discharge into the aquatic system is extremely necessary. In this study, the nonlinear regression method was used to determine the kinetic and isotherm...
L-Ascorbic acid, commonly referred to as Vitamin C, is a water-soluble molecule renowned for its remarkable antioxidant properties1. In this form it is susceptible to physico-chemical changes caused by a change in temperature, moisture, light and oxygen2, and can often easily form metal ascorbate salts3. Among these salts, magnesium, sodium, and calcium ascorbate are particularly renowned and...
Terpenes are cannabis secondary metabolites that provide not only beneficial biological properties for the plant, but also are found to have synergic and/or enhancing effects of the cannabinoids1. Therefore, they are extremely important in the production of pharmaceuticals significant for the improvement of human health1. To emphasize, terpenes are volatile compounds that produce the plant its...
Method optimization and validation for particle size distribution for Cefixime trihydrate using Malvern Mastersizer 3000
Method validation for in situ identification of diazepam with Raman spectroscopy in pharmaceutical industry
The kinetics and mechanism of cathodic electrodeposition of bismuth on a glassy carbon (GC) electrode were studied using cyclic voltammetry and chronoamperometry. The initial phase of bismuth electrodeposition was studied using the potentiostatic pulse technique in different electrolytes (nitric acid and acetate buffer solution) with and without the addition of EDTA as a complexing agent. A...
The following investigation presents the thermal treatment of geopolymer based on metakaolin, with the addition of 1% and 5% of neodymium in the form Nd2O3, at 300˚C, 600˚C and 900˚C. Six samples were synthesized in total. Samples GT1 and GT2 containing 1% and 5% of Nd2O3, and they were treated at 300˚C, while the samples GT3 and GT4 also had the same percentage composition of Nd2O3 and were...
We offer a contribution to methodology of targeting important regulatory nucleic acid structures, G-quadruplexes. A model of their interaction with potentially anticancer hetero-polycyclic molecules is developed using methods of its precision computation by quantum chemistry.1 Further we use quantitative characterizations of biological activity of studied heterocycles.2 We find meaningful...
Epoxy resin has wide applications due to its exceptional chemical resistance, toughness characteristics, and bonding effects. The epoxy-matrix composites are predominantly used in the design of high-performance materials1. Thus, studying the properties of composite materials based on epoxy resin matrix is highly suggested in order to enhance their characteristics.
The effect of modified epoxy...
The possibility of utilizing waste lignocellulosic fibers for the removal of selected sedative residues from polluted water was investigated as an attempt to reuse textile waste and reduce its disposal costs. To increase the adsorption efficiency, waste hemp (H) and flax (F) fibers were modified with a benzoyl peroxide solution. Unmodified and modified fibers (HBP and FBP) were characterized...
The immense quantity of industrial waste is a global problem that requires new solutions in accordance with the principles of circular economy and sustainable development. Therefore, in this work, fly ash obtained as waste from thermal power plants was used as an adsorbent for the removal of pharmaceutical residues from water. To improve the adsorption efficiency of fly ash, different...
Ligands with multiple coordination sites are often used in the synthesis of the extended metallo-organic structures. Both pyrazolyl and acetato ligands can have a role of a ''bridge'' between the metallo-organic fragments. As a part of the study of the coordination capabilities of pyrazole-based ligands we are reporting the molecular and crystal structure of the...
Experimental data of liquid binary mixtures can provide the thermodynamic and transport properties1. Molecular dynamics simulations (MD) are preformed on the same mixtures at the same experimental conditions: at different temperatures and different mixture compositions. Molecular dynamics simulations can gain a deeper understanding of the behavior of liquid mixtures at the molecular level. It...
Mechanochemical activation is an effective method for obtaining uniform, nano-sized and surface-activated powders. It increases the energy of the system, affecting the morphology of the particles, and hence the thermal properties of the materials and often leads to the formation of new phases.
The effect of the revolutions and duration of the mechanochemical activation on the properties of...
The demand for clothes with antimicrobial and UV protective properties is continually growing. In an attempt to develop a simple and efficient treatment for cotton fabrics, layer-by-layer deposition of chitosan and magnesium lignosulfonate followed by in situ synthesis of Ag nanoparticles (NPs) was performed. Magnesium lignosulfonate acts as a stabilizing agent and UV blocker while NaBH4 is...
Partial least squares‒discriminant analysis (PLS-DA)1 using Simca® 17 software was applied for evaluation of the results obtained from a compatibility study designed for the active pharmaceutical ingredient (API) ibuprofen with selection of twelve excipients used in the formulation of pharmaceutical finished products. Fourier-transform infrared spectroscopy (FTIR) and X-Ray powder diffraction...
Poly(vinylidene difluoride), PVDF as a semi-crystalline polymer was widely investigated due to its ferro-, pyro- and piezoelectric behavior, combined with its excellent flexibility and mechanical properties1. The piezoelectric activity of this polymer is primarily dependent on the development of a specific crystal β-phase. Various procedures and post-treatments have been proposed for achieving...
Due to their high surface-to-volume ratio nanomaterials are highly interesting candidates as functional materials for chemical sensors. Furthermore, using composites enable tuning of the materials properties to allow the formation of sensor arrays, and that can be used for many different applications including industrial process, food and environmental monitoring as well as for medical...
Oxyimino ethers are compounds very often used in organic synthesis to obtain various products such as amino alcohols, hydroxylamines and amines, but they have also shown promising anticancer activity.1 Bearing this in mind, we have efficiently synthesized a new O-alkylated oxime derivative in the androstane series, which was then used as a precursor for preparing a...
The genus Doronicum (Asteraceae) comprises 26 different plant species, mostly distributed in Europe and southwest Asia. Although some of the monoterpenoids, sesquiterpenoids, and diterpenoids from Doronicum species possess significant biological activity, the genus is still poorly phytochemically and pharmacologically studied. Doronicum columnae Ten. is a perennial representative of this...
Hybrid molecules created by combining a steroid with a thiazole core may be potential candidates for drug design, with improved biological activity and bioavailability. This work describes the synthesis of new thiazole androstane derivatives. The starting compound was dehydroepiandrosterone, which was modified in a multiphase synthesis into 3- or 6-thiosemicarbazone androstane derivatives,...
Numerous chemicals have entered the environment for decades of industrialization and urbanization from a variety of anthropogenic sources. Currently, more than 350,000 chemicals have been registered for commercial use worldwide, with even more new chemicals expected to appear in the future. Only a small fraction of them, accounting for (far) less than 1%, has been routinely monitored in the...
Structural and morphological properties of CH3NH3PbI3 thin films deposited by spin coating, with different spin speeds on glass and ITO patterned substrates were investigated. It results that long length acicular crystals, growth parallel to substrates (> 200m for spin speeds of 800RPM/min). For low deposition spin speed these crystals are interconnected and deposited films present high...
In 1923, Peter Debye and Erich Hückel published a paper in which they derived a simple equation that could be used to quantitatively predict mean activity coefficients of electrolytes in dilute aqueous solutions [1]. The equation soon became one of the most widely used equations in analytical and physical chemistry and was soon adapted also for calculation of many other thermodynamical and...
Compared to alternative wastewater treatment methods such as adsorption, coagulation/flocculation, usage of aerated/aerobic lagoons, and many others that enable the removal of certain types of contaminants and the creation of a large amount of waste at the end of the process, membrane pressure processes enable the removal of a wide range of contaminants and the generation of very small amounts...
Anticancer drugs can cause serious health hazards such as organ toxicity and drug resistance because of their high potency if not properly dosed. Have a reliable method for concentration monitoring and detection of trace amounts of anticancer drugs in biological samples is of great importance for narrowing the gap between the therapeutical and toxic doses. The need for rapid and sensitive...
Advancements in technology often rely on the development or enhancement of materials. Bacterial nanocellulose (BNC) has found diverse applications in fields such as biomedicine, ecology, and electronics, leading to increased interest in BNC-based composites1,2. Understanding the synthesis parameters that affect the crystal structure and morphology of these composites is crucial, as it directly...
Throughout the centuries, various botanicals have been utilized as additives in beer for different purposes, including their preservative properties, perceived medical benefits, desired psychotropic effects or simply for enjoyable flavors.1
A study was conducted to determine the taste and appearance of laboratory-made beers infused with nettle (Urtica dioica), sage (Salvia officinalis) and...
Dopamine and serotonin are main neurotransmitters that maintain excellent mental wellbeing and regulate physiological functions in human tissues. Oxidation of both neurotransmitters is of great importance in understanding their mechanisms of actions in the human body. This scientific study reveals the most probable oxidation mechanisms of these neurotransmitters in simulated physiological...
We report a study on the electrochemical properties of a peptide molecular wire used as both conductive support for immobilizing ligands in affinity-based bioassays and as signal amplifier for the ultrasensitive detection of H2O2 in biological samples. A short helical peptide sequence with alternating polar and ionizable side chains was synthesized to modify the surface of the biosensor. The...
Biotechnology and food technology (BFT)
The investigations on next generation of electrode materials that should meet the increasing requirements for high power, safety, low cost and environmental compatibility are a hot research topic in the field of energy storage. Iron containing phosphate-based electrode materials offer a great promise for large scale application due to high structural and thermal stability, good cycling...
Titanium dioxide is a n-type semiconductor and due to its wide optical band gap (Eg~ 3.3 eV) has numerous applications in various scientific areas such as photocatalysis, sensors, energy harvesting, etc. Its photocatalytic properties have been used in a big number of environmental applications focusing on the removal of contaminants from water. Degussa P25, is a titania photocatalyst in the...
Recently, there has been a growing interest in mixing two different systems, organic and inorganic, which would contribute to some improved properties, such as adjustment time, reduced shrinkage, improved mechanical properties and durability. A new class of geopolymer composites with an organic matrix has been developed with the main goal of improving the fire resistance of organic polymers...
Whey is the yellow liquid byproduct obtained at cheese production. It is characterized by several commercial applications, mainly for whey cheese. In the dairy industry, the term „Scotta“ is used for the whey separated after whey cheese production. Because of its high availability and high-value compoundssuch as proteins, peptides, and lactose, scotta could be used in the food and...
The aim of this study was determination of physical-chemical, radiological and structural characteristics of kaolin, fly ash and products of alkali-activated as well as thermally treated kaolin (alkali activated materials). Also, the objective of presented research was application in the field of construction and civil engineering as green cements. The objective of presented research was to...
Phytochemicals are essential components of traditional knowledge systems in complementary and alternative medicine, nutraceutical, food supplements, and pharmaceuticals. Bioactive secondary metabolites can be classified as phenolics, terpenes and steroids, and nitrogen compounds including alkaloids. Each of these classes contains a very large and diverse set of compounds that have a very wide...
Studies for volatile organic compounds (VOC) in urban areas in the southern Balkans are scarce and our objective was to monitor the organic emissions in outdoor air in seven cities in Kosova for several months using Radiello® diffusive passive samplers. In parallel, the profile of VOC from commercially available gasoline and diesel fuels in the respective cities was determined using static...
The use of compounds for corrosion protection such as chromates and some synthetic organic substances is prohibited or restricted due to their hazardous and carcinogenic nature. Recently, research has been focused on green corrosion inhibitors, whose name is mostly associated with plant essential oils and extracts that are environmentally friendly, non-toxic, inexpensive, not harmful to human...
The adsorption of polycarboxy or polysulfo betaine on the double doped (with Zn and Mg) amorphous calcium phosphate (ACP) was studied with the aim of preparation of functionalized materials with improved remineralizing activity for dental applications. ACP is a precursor for the formation of the teeth and bone mineral phase. Mg and Zn are essential for the building and growth of hard tissues...
Polycyclic aromatic hydrocarbons (PAHs) are amongst the most toxic compounds known to man. Several PAHs are proven to be carcinogenic, mutagenic, and teratogenic. Due to their wide distribution in the environment and their toxicity, it is considered important to monitor the levels of these compounds in foodstuff. PAHs have been detected in many foods including plant-based such as vegetable...
Polymers are a wide group of materials that have quite a wide range of applications due to their diverse properties. Their properties depend on their chemical structure, morphology, method of synthesis and processing. Since there are many variables that affect their characteristics, the characterization of these materials can be lengthy process.
In order to overcome this problem,...
Due to the low CO2 emission of geopolymers compared to Portland cement, interest in their use as binding cement has increased in recent years. The main goal of this research is to relate the green and sustainable characteristics to the good mechanical and chemical properties of fly ash-based geopolymers. For those purposes, samples of different ratios of fly ash (FA) and metakaolin (MK) were...
Tobacco stalks,as agricultural waste, due to the lignocellulosic composition can be evaluated as a potential raw material in bioethanol production. Pretreatment of lignocellulosic materials is the first step in the bioconversion process utilized to break down the lignin, open up the crystalline structure of cellulose, and its hydrolysis to sugars by application of acids or enzymes.1
The...
Herein we describe a program written in Python programming language that employs a simple complete-search algorithm for determining the geometry of a lanthanide-substrate (LS) complex. The program can be used as a work project in an introductory programming course for chemistry students to illustrate the concepts such as decision-making, repetition, functions, lists, file reading, and data...
Alkaloid AD Skopje, within the Chemistry Program has a long tradition in the production of pure chemicals. This group of products, also includes silver salts. Currently we manufacture the following silver salts: silver nitrate, silver sulfate, silver iodide and silver cyanide. The quality of these products ranges from reagent grade, pro analysi, Ph.Eur., USP and special quality requirements...
Energy consumption and its effects on the environment is a popular topic nowadays and it has triggered many experts to work hard on possible solutions. Probably the best and most cost-efficient outcomes are passive and energy-free technologies, such as smart windows with thermochromic properties.
A key material for the production of thermochromic varnishes is believed to be W-doped vanadium...
The focus of this research work was to evaluate the potential of G/CNT based polymer composites to be used as protective coatings for outdoor application. In order to perform that, graphene/carbon nanotubes (G/CNT) based polymer composite was synthetized via miniemulsion polymerization. The weight ratio of G and CNT was 10:1, while the concentration of the G/CNT hybrid filler with respect to...
RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase) is a non-allergenic, easily digestible protein found in the leaves of C3 plants, accounting for up to 50% of the total. It is similar to the FAO's ideal protein and is offered as a valuable alternative for meeting nutritional requirements. Plant-based proteins provide amino acids for human cells development and act as precursors of...
Sulfonylureas inhibit the biosynthesis of branched-chain amino acids in plants by inhibiting the enzyme ALS, and are widely used worldwide for selective weed control in various field-crops such as wheat, cotton, oil seed rape and corn, orchards (such olive groves) and vegetables (including tomato and potato) in pre-planting and post-planting applications. Some of these herbicides are highly...
Contemporary literature does not explain the infrared and vibrational circular dichroism (VCD) spectra of chiral molecules from a classical perspective.1,2 As a result, the primary usage of VCD spectra is to determine the absolute configuration of a chiral molecule through comparison of experimental data and quantum mechanical calculations. Classical treatments of IR and VCD spectra can...
The focus of nanoscience and nanotechnology is gradually shifting from individual nanostructures to their assemblies in which these nanostructures mutually interact and organize into nanostructured materials with new collective properties and remarkable applications in a wide range of fields (such as medical diagnostics, drug delivery, sensors, electronic devices etc.). Currently, in this...
A series of MgxFe3-xO4 (x = 0, 0.1, 0.2, 0.4, 0.6, 0.8, and 1) magnetic nanoparticles (MNP) were synthesized by a two-step procedure, a co-precipitation method followed by hydrothermal treatment in a microwave field. The MNP are single-core, with crystallite size gradually decreasing from 15.5(3) up to 2.5(3) nm with an increase of x. TEM images show pseudospherical log-normally distributed...
The monitoring of pesticide residues in cereal-based products is important to ensure food safety and compliance with maximum residue levels (MRLs) enforced by the current legislation [1]. In this study a rapid GC-MS/MS method was validated for simultaneous analysis of 95 pesticides in cereal-based products. The samples, fortified with triphenyl phosphate (Sigma-Aldrich, Saint Louis, USA) as an...
The construction industry is one of the most resource-intensive economic sectors in the world. In the EU, it is responsible for using around 50% of all raw materials mined. 90% of the raw materials used are non-renewable mineral raw materials such as stones, gravel and sand. Their mining causes extensive interventions in nature and landscape.
At the same time, the construction sector produces...
Accumulation of waste represents one of the biggest problems of modern civilization, from the energy, construction, urban, ecological and technological point of view. In this work, fly ash, as waste material from the power plant Nikola Tesla, was activated with sodium hydroxide at elevated temperature and then chemically modified with different amounts of polyethylenimine (PEI). The...
2,6-Cyclocuparan-3-ols are chemical markers and major volatiles of several liverwort species. Conflicting reports on the structures of these cyclocuparanols can be found in the literature–different research groups assigned the same spectral data to different structures, yet these inconsistencies were never addressed, let alone satisfactorily explained. Following the isolation of all four...
The use of food additives has been practiced a long time ago, in order to perform a specific function. So, for example, food preservatives are added to extend the shelf life of food products, artificial sweeteners are added to replace sugars, while stimulants are added to increase consumer alertness.
This study presents a developed and validated reversed-phase high-performance liquid...
Malathion is one of the most commonly used organophosphorus insecticides both in our country and world-wide. Its use is also approved in the countries of the European Union1. It is an active substance of the pesticide formulation Etiol techni, which is in the form of an emulsion concentrate (EC).
The development of new analytical methods for the determination of active substances in plant...
Smart specialization strategy (S3) presents a modern approach to economic development based on knowledge, research and innovation, thus connecting science and business. Sustainable Development Goals (SDGs) and EU Green Deal present the main pillars of S3. According to the EU Green Deal, there are need, more than any time before, to apply the circular economy concept and the principles for...
Hydrazone-type compounds are known for their versatile biological activities.1 This encouraged us to subject six phenolic hydrazones (1-6) to in silico investigation of potential antiviral activity against SARS-CoV-2. For this purpose, molecular docking was performed on the protein involved in viral reproduction processes main protease (Mpro).2
The obtained results revealed that all...
The cobalt oxide (Co3O4) is a very attractive material for optoelectronic applications due to the intense absorption of visible light and p-type semiconducting properties. On the other hand, conventional synthesis methods for its preparation could be either time- and energy-consuming or relying on toxic chemicals. To address this issue, spinel Co3O4 nanoparticles were prepared by a simple,...
Abstract
The surging trend of plant-based food regimen has stimulated the innovation and improvement of alternative meat products. In this regard, meat analogues such as veggie burgers have emerged as a notable choice for consumers that are perpetually seeking for healthier and more environmentally sustainable dietary choices1-4.
In order to successfully incorporate these analogues into...
In previous decades advanced biotechnological techniques, including transgenesis, enables the precise and efficient targeted modification of an organism’s genome. However, when it comes to the food production, very few topics in science raised so much controversy as that of genetically modified organisms, or GMOs. As GMOs are generated through the transgenic introduction of foreign DNA...
Silver nanoplates, either in trigonal or hexagonal morphology, are crystals formed due to the stacking faults in a crystal lattice, resulting in highly asymmetric crystals of otherwise cubic silver morphology. Because of that they exhibit pronounced plasmonic properties also in visible spectra. As such they are attractive material for various applications like enhance sensors or as...
Sodium periodate oxidation of raw jute fabric – A novel approach for tuning the jute structure and properties
A. Ivanovska,a M. Miloševićb, J. Lađarevićb, B. Dojčinovićc, T. Matića, N. Baraća, M. Kostićb
aUniversity of Belgrade, Innovation Center of the Faculty of Technology and Metallurgy, 11000 Belgrade, Serbia
bUniversity of Belgrade, Faculty of Technology and Metallurgy, 11000 Belgrade,...
Air quality is one of the key factors that determine human health and longevity. The air that we breathe can be contaminated with various impurities such as; sulfur oxides (SOX), carbon monoxide (CO), ozone (O3) and the volatile organic compounds (VOCs).1 The primary idea of this work was to achieve the synergistic action between immobilized photocatalyst titanium dioxide, TiO2, on the surface...
High-performance liquid chromatography with diode array detection (HPLC-DAD) was used to study the stability of individual anthocyanins during preparation of raspberry sugar jam and sugar-low jam at high temperatures (90, 95, 100 and 105 °C).
The preparation of sugar jam implied 60% of fruit puree, 30% of saccharose, 9.8% of glucose and 0.2% of commercially available pectin. The preparation...
The textile industry effluents containing various types of synthetic dyes is one of the significant cause of water contamination and pose a serious threat to the natural ecosystem. More than one hundred different types of dyes are commercially available that are used in the annual production of over 80 million tons of textile fabrics globally, and the annual cumulative consumption of dyes...
As the industrial requirements change at a rapid pace due to the drastic evolution of technology, the necessity of a more efficient manufacturing system arises more intensely than ever.
The concentrates for haemodialysis are alkaline and acidic solutions of inorganic salts with or without glucose and are used to treat patients with kidney insufficiency or failure (acute and chronic). The...
The aim of this paper is to show the possibility of using waste materials, a mixture of wood ash and fly ash and metakaolin for the production of alkali activated materials that can be used to purify wastewater from different kinds of pollutants such as heavy metals for example. Heavy metals, can be very toxic, especially cadmium, so they must be removed from wastewater to prevent or minimize...
There has been a steady increase in demand for functional materials for applications not only in public buildings, but also in households. The common use of antibiotics has contributed to antibiotic resistance among many strains of bacteria and fungi. A solution to this problem may be the synthesis of composites with antimicrobial properties. The materials produced will be able to be used as...
The electrocatalytic oxidation of small organic molecules, such as methanol, ethanol and formic acid has been extensively studied due to their properties that make them suitable for use in fuel cells. Particularly, the electrochemical oxidation of formic acid has been comprehensively examined as the anodic reaction in direct formic acid fuel cell. The main goal in the development of the...
Hybrid organic-inorganic perovskites (HOIPs) have been an intensely studied class of materials since the synthesis of the seminal compound (CH3NH3)PbI3, due to their promising optoelectronic properties and their potential application in the design of diodes, photosensors and photovoltaic cells. In this work, we describe the synthesis and characterization of a class of iodide organic-inorganic...
Aniline, the main representative of aromatic amines, occurs in a large number of industries, such as the production of textiles, plastics, medicines, pesticides, rubber, and varnishes.1 Due to practicality and efficiency, a molecularly imprinted polymers (MIPs) can be used as sorbents for removing aniline.2 In this study, magnetic molecularly imprinted polymer was synthesized via suspension...
The rare-earth perovskite oxides containing 3d transition metals are considered as important materials due to their specific electronic, magnetic, optical and catalytic properties. These properties are even more pronounced in complex perovskites, particularly those with manganese in the B-position. Continuing our work on complex perovskites, in this work we present the synthesis and...
In recent years, perovskites that contain two different lanthanides in the A-position have garnered significant attention due to the ability of these elements to introduce exceptional properties and functionalities to the versatile perovskite framework. Lanthanides, which exhibit unique and distinctive electronic configurations and magnetic moments, offer opportunities for precise tuning of...
Lignin is natural polymer characteristic for its antioxidative and fire-retardant properties. In this research work lignin was used as filler for synthesis of polymer composites via in-situ miniemulsion polymerization. As monomer system were used methyl methacrylate and butyl acrylate in 50:50 weight ration. Lignin was added in 1wt%, 2 wt% and 3 wt% relative to monomers. The incorporation of...
Hydrazone core represents a valuable pharmacophore in medicinal chemistry and drug design.1 The ease of synthetic transformations and their tunability granted hydrazone-type compounds diverse activities of biological importance.2 In this work, the synthesis of five novel phenolic hydrazones was performed in the reactions of 2,3,4-trihydroxybenzohydrazide with various aromatic aldehydes.
...
Multiple tumors have been proven to be hormone-dependent, meaning that their development and growth are induced by endogenous human hormones. This fact was the basis for the design and development of antitumor steroidal drugs such as testolactone and exemestane. With the same goal in mind, we have performed a synthesis of C19-halogenated steroidal D-homo lactones. Previously synthesized...
Starch belongs to the group of polysaccharides of plant origin. It is composed of glucose mers linked by α-glycosidic bonds and acts as an energy store in plants. Starch is a very interesting biopolymer, the possibilities for its use in sorption processes being created by its very interesting structure resulting from the presence of hydroxyl groups. The undoubted advantages of using starch are...
Incorporation of alternative plant protein concentrates or isolates into cereal-based matrices can lead to the production of nutritionally improved products such as bread with high protein content and improved essential amino acid profile, especially lysine. Green leaves, as the richest protein source containing soluble – white and insoluble – green proteins, seem to be an attractive and...
Arthrospira platensis is an edible blue-green alga that shows beneficial activities in humans and animals. Biotreatment/biotransformation with lactic acid bacteria (LAB) is a popular solution to degrade plant and cyanobacterial cell walls, to produce smaller molecules with enhanced (immunomodulatory, antioxidant, antimicrobial, etc.) properties. Additionally, via peptide bond hydrolysis, LAB...
The aim of this research paper is to determine the changes in mechanical properties of products when certain changes are made within the resin system that they are produced with
With this goal in mind, the polymer composite materials1 which were used in this research effort were obtained via pultrusion2. The products are cylindrical in shape and are mainly...
Water vapour permeability, often expressed as evaporation resistance Ret, belongs to the most important thermal comfort parameters of protective, sport and other functional clothing (garments) and related textile fabrics. Water vapour permeability of all textile products should be as high as possible, in order to prevent the accumulation of sweat in the garment system and simulatenously...
Amazon rainforest is one of the most significant biodiversity hotspots in the world and represents a phytochemical gold mine with countless plant species with immense pharmacological potential.1 One of them is paracress (Acmella oleracea (L.) R. K. Jansen (Asteraceae)) with already proven pharmacological properties including, but not limited to antinociceptive, anti-inflammatory,...
Metallocarbonyl complexes, also known as carbon monoxide releasing molecules (CORMs), containing imides can serve as novel compounds to overcome antibiotic resistance. CORM interfere with cell wall biosynthesis, target cytoplasmic membrane, depolarize membranes, and induce oxidative stress [1]. They are characterized by anti-inflammatory, anti-apoptotic, anti-atherosclerotic,...
Pyrethroid pesticides are substances of intense interest for use in tobacco protection because of their desirable environmental properties of short persistence and nontoxicity to mammals. These features combined with their broad spectrum of pesticidal activity have made the pyrethroids alternatives to the older organochlorine compounds and the natural pyrethrins. The main aim of this...
Pharmaceutical Chemical Cosmetic Industry ALKALOID AD Skopje plays an important role in the circular economy. One part of this industry encompasses production of a wide range of chemicals intended for laboratory, industry and consumer use, products used for agriculture production, cleaning agents and disinfectants.
Maintaining quality is essential to delivering quality, safe and efficient...
Section: 8. Textile engineering (TE)
Urban lakes sediments unfortunately have received a large amount of wastewater containing various contaminants such as heavy metals (HMs). Heavy metals in urban lake sediments mainly originate from industrial discharge, heating sources, traffic emissions and waste from municipal activities. The human health and the whole ecosystems are threatened with potential harmful effects of following...
Fluorine-18 radiopharmaceuticals are drug molecules that contain the positron-emitting (β+) radioisotope [18F]F. As a favorable halogen atom in radiopharmaceutical chemistry, [18F]F is suitable for the development of many radiopharmaceuticals, intended for investigating tumors by positron emission tomography (PET).
The utilization of nucleophilic [18F]F− ions in the fluorine-18...
Topic: Organic chemistry, biochemistry and pharmaceutical chemistry
The use of proteins as active cosmetic substances dates back to ancient times, the reason for their use in cosmetic preparations is that they have been found to improve skin that is old (mature skin with visible signs of aging), have a positive effect on hair and nails. The use of proteins in cosmetic preparations...
Fluorescent polymers are functional macromolecules with very important applications1. One of the traditional methods for their synthesis is by copolymerization of traditional monomers with fluorescent monomers (unsaturated fluorescent dyes). Among them, naphthalimide derivatives are attracting much attention due to their excellent stability, photophysical, thermal, electrochemical and...
Electrochemiluminescence (ECL) is the light emission triggered by an electrochemical reaction at the electrode surface [1-2]. Since ECL is based on an “electro-excitation” process, it does not require any light source to generate the light as in fluorescence. Thus, ECL combines intimately electrochemistry and photophysics. Due to the orthogonal modalities of electrochemical stimulation and...
Polyurethane networks (PUNs) based on hyperbranched polyesters (HBP), polycaprolactone (PCL), and isophorone diisocyanate were prepared.1,2 PUNs consist of different content of hard (HS) and soft segments (SS). The impact of the HBP and the content of the SS on the structure and viscoelastic properties of the prepared PUNs were investigated. XRD analysis confirmed that PUNs with lower SS...
Lavender flowers as well as essential oil are often used as herbal remedy for nervous disturbance, anxiety, mild depression and aromatherapy1. GC/MS method was used for identification of volatile compounds in Lavandula aetheroleum. Cytotoxic activity was determined using the Brine shrimp lethality assay (BSLA)2,3. Meyer's and Clarkson's scales were used to categorize the essential oil...
The aim of this study was to investigate the influence of different commercial inactivated yeast derivatives (IYDs) on the volatile profile of wine during aging. The study was performed with Grašac grapes from Srem wine region (Serbia). After fermentation was complete, wine samples were treated with different IYDs in two doses. After the six-month aging period, wine samples were analyzed for...
Flavonoids, widely distributed second metabolites of plants, have a large number of functions. Nowadays, with more nature-oriented lifestyle, the role in plants and potential benefits for humans and animals became more and more important.1
3-Hydroxyflavone (3HF) represents the backbone of all flavonols, a widespread class of flavonoids. Interestingly, this compound is not found naturally in...
