20–23 Sept 2023
Metropol Lake Resort, Ohrid
Europe/Skopje timezone

Determination of antimicrobial activity of copper activated macroporous GMA based copolymer

Not scheduled
20m
Metropol Lake Resort, Ohrid

Metropol Lake Resort, Ohrid

Poster presentation

Speaker

Sandra Bulatović (University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Belgrade, Serbia)

Description

Macroporous (glycidyl methacrylate) GMA-based composite was synthesized via suspension polymerization in the presence of 2 wt. % magnetic nanoparticles and functionalized with triethylenetetramine. Copper was immobilized on composite by contacting modified copolymer with 0.1 M solution of CuCl2, at pH 5, and 25 ̊C. The obtained composite was characterized by mercury porosimetry, Fourier transform infrared spectroscopy (FTIR) analysis and atomic force microscopy (AFM). GMA-based composites, due to their properties (size, porosity, etc.), and the presence of reactive epoxy group, have found a variety of applications as sorbents, enzyme supports, in biomedical applications, for metal and organic compounds sorption.1
The antimicrobial activity of the synthesized GMA/Cu copolymer against Staphylococcus aureus, Escherichia coli, Candida albicans and Aspergillus niger as representatives for Gram-positive bacteria, Gram-negative bacteria, yeast and fungi were investigated in this study.2 The copolymer displayed good antimicrobial activity against all analyzed microbes, which makes it a material that can be potentially used for biomedical (antibacterial and antifungal) applications.

Acknowledgement: This research has been financially supported by the Ministry of Science, Technological Development and Innovation of Republic of Serbia (Contract No: 451-03-47/2023-01/200026 and 451-03-47/2023-01/200168).
References:
1. Marković, B. M.; Spasojević, V. V.; Dapčević, A.; Vuković, Z. M.; Pavlović, V. B.; Ranđelović, D. V.; Nastasović, A. B., Characterization of glycidyl methacrylate based magnetic nanocomposites, Hem. Ind. 2019, 73(1), 25-35. DOI: 10.2298/HEMIND181113006M
2. Nguyen, V. T.; Vu, V. T.; Nguyen, T. H.; Nguyen, T. A.; Tran, V. K.; Nguyen-Tri, P., Antibacterial Activity of TiO2- and ZnO-Decorated with Silver Nanoparticles, J. Compos. Sci. 2019, 3(2), 61. DOI: 10.3390/jcs3020061

Primary author

Sandra Bulatović (University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Belgrade, Serbia)

Co-authors

Dr Bojana Marković (University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Belgrade, Serbia) Mrs Tamara Tadić (University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Belgrade, Serbia) Dr Aleksandra Nastasović (University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Belgrade, Serbia) Dr Mila Ilić (University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Belgrade, Serbia) Dr Danijela Randjelović (University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Belgrade, Serbia) Natalija Nedić (University of Belgrade, Faculty of Chemistry, Belgrade, Serbia)

Presentation materials