23–26 Sept 2026
Metropol Lake Resort
Europe/Zurich timezone

Optimization and Application of a Method for Determining the Aromatic Profile of Macedonian White Wines Using Gas Chromatography Coupled with Mass Spectrometry

Not scheduled
10m
Metropol Lake Resort

Metropol Lake Resort

Naselba Dolno Konjsko bb, 6000 Ohrid, N. Macedonia
E-poster Analytical and environmental chemistry

Speaker

Hristina Trisheska

Description

Wine aroma is one of the most important characteristics of wine quality and is determined by a complex mixture of volatile compounds. In this work, volatile aromatic compounds in Macedonian white wines were investigated using gas chromatography coupled with mass spectrometry (GC-MS) and two capillary columns with different stationary-phase polarities (HP5-MS with 5 % phenyl, and DB-1701 with 14 % - cyanopropyl-phenyl. Liquid-liquid extraction with dichloromethane was selected as the most suitable sample preparation procedure and was subsequently optimized to obtain optimal extraction conditions starting from 10 mL of wine and 1 mL dichloromethane and addition of 1 g of (NH4)2SO4 for pH control and 1-octanol as an internal standard.
The developed method was tested with a standard mixture of alcohols, esters, acids and terpenes and showed good sensitivity and reproducibility, with LOD values between 0.04 and 0.29 µg/mL and LOQ values of 0.41–2.93 µg/mL. Most investigated compounds showed RSD values below 10 %, indicating good analytical precision. The two columns showed complementary chromatographic characteristics. HP-5MS provided better detection of less polar compounds, particularly terpenes and long-chain ethyl esters, while DB-1701 showed improved detection and peak shape for more polar compounds, especially for carboxylic acids.
Application of the method to different Macedonian white wine varieties revealed a complex profile of alcohols, esters, terpenes, and carboxylic acids. Hexan-1-ol,
2-phenylethanol, isoamyl acetate, and several ethyl esters were consistently detected and represented important components of the wine aroma. The results demonstrate that the combined use of HP-5MS and DB-1701 enables more reliable identification and comprehensive characterization of the different classes of volatile aromatic compounds in Macedonian white wines.

Authors

Hristina Trisheska Marina Stefova (Institute of Chemistry, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University in Skopje)

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