28th Congress of SCTM

Contribution List

13. Chemistry Matters: From a Putative Peptide to Effective Medicines for Diabetes and Obesity

Dr Svetlana Mojsov (Rockefeller University, New York, USA)

Organic chemistry, biochemistry and pharmaceutical chemistry

Lecture

In the 1960s and 1970s, considerable interest was directed toward understanding the role of peptides in glucose metabolism. Particular attention was given to incretins, intestinally secreted peptides that stimulate insulin release from pancreatic β-cells following food intake, thereby regulating glucose homeostasis. In parallel, research efforts focused on glucagon, a peptide secreted by...