Speaker
Description
The demand for new wound dressings is rising to overcome the limitations of traditional treatments. Hydrogels, known for their low toxicity, biocompatibility, and wound-healing properties, have emerged as promising candidates, while grape skins offer a valuable source of bioactive compounds for incorporation into such vehicle. Therefore, we aimed to formulate grape skin extract-based hydrogels with various alginate/gelatin ratio utilizing a simple crosslinking method involving freezing and higher concentrations of CaCl2 as the crosslinking agent. Hydrogel formulations were subjected to swelling studies and determination of the release of bioactive compounds to identify the optimal formulation for potential use in wound healing. Our findings suggest that increasing the gelatin content in the hydrogels resulted in a noticeable decrease in swelling capacity. Moreover, grape skin extract-based hydrogel released compounds up to 24 hours. Developed hydrogels possesses properties suitable for wound care application.
| Scientific Sections | Sustainable and bio-based polymer materials |
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