Dr
Aleksandar Kocovic
(Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Center of Excellence for Redox Balance Research in Cardiovascular and Metabolic Disorders, Kragujevac, Serbia)
There is a constant need to improve medicinal forms both in terms of pharmaceutical and technological characteristics and in terms of efficacy. Hydrogels are among the most studied dosage forms when it comes to wound healing, due to their favorable technological characteristics, controlled release at the site of application and the possibility of incorporating various medicinal substances. In addition, the reuse of some by-products of technological processes, such as grape skins after wine production, represents a contribution in environmental terms. The aim of the research was to examine the antioxidant effect of hydrogels enriched with grape skin extracts obtained using environmentally friendly solvents. The results show that the prepared hydrogels achieve a moderate antioxidant effect under simulated physiological conditions. The antioxidant effect is important both for achieving a therapeutic effect and for preventing deterioration of the stability of the preparation itself.
| Scientific Sections |
Sustainable and bio-based polymer materials
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Dr
Aleksandar Kocovic
(Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Center of Excellence for Redox Balance Research in Cardiovascular and Metabolic Disorders, Kragujevac, Serbia)
Prof.
Jovana Bradic
(Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Center of Excellence for Redox Balance Research in Cardiovascular and Metabolic Disorders, Kragujevac, Serbia)
Prof.
Anica Petrovic
(Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Center of Excellence for Redox Balance Research in Cardiovascular and Metabolic Disorders, Kragujevac, Serbia)
Mr
Marko Simic
(Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Center of Excellence for Redox Balance Research in Cardiovascular and Metabolic Disorders, Kragujevac, Serbia)
Dr
Edina Avdovic
(Institute for Information Technologies, Kragujevac, University of Kragujevac, Kragujevac, Serbia)
Prof.
Vladimir Jakovljevic
(Center of Excellence for Redox Balance Research in Cardiovascular and Metabolic Disorders, Kragujevac, Serbia, Department of Physiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia, Department of Human Pathology, I.M. Sechenov First Moscow State Medical University, Moscow, Russia)
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