-
Mrs Nadja Ilic (University of Nis, Faculty of Technology, Bulevar oslobodjenja 124, 16000 Leskovac, Serbia), Jana Cvetkovic (University of Nis, Faculty of Technology)24/09/2026, 16:45Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Grape pomace represents an important winery by-product with significant potential for valorization as a source of minerals and bioactive compounds. In this study, an aqueous extract of grape pomace obtained from the autochthonous Serbian cultivar Prokupac was analyzed in order to evaluate its mineral profile determinate by ICP-OES method and phytochemical composition determined by LCโMS...
Go to contribution page -
Blagica Janeva (Institute of Chemistry, Faculty of Natural Sciences & Mathematics, Ss. Cyril and Methodius University in Skopje N. Macedonia)24/09/2026, 16:50Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Species of the genus Stachys (Lamiaceae) are widely distributed medicinal and aromatic plants characterized by considerable morphological diversity and rich phytochemical composition. Molecular identification of Stachys species requires high-quality DNA. However, the presence of secondary metabolites, particularly polyphenols, may interfere with DNA isolation and downstream molecular analyses....
Go to contribution page -
Maja Sencheva Petrevska (Institute of Organic Technology, Faculty of Technology and Metallurgy, Ss. Cyril and Methodius University in Skopje, Skopje, North Macedonia)24/09/2026, 16:55Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Pelargonium graveolens L. is a medicinal and aromatic plant known to possess phenolic compounds with significant antioxidant potential. The extraction efficiency of these bioactive compounds depends on several experimental parameters such as the type of extraction, the solvent used for extraction, the characteristics of the plant material and the solvent-solid ratio.1,2 The aim of this study...
Go to contribution page -
Lavinia Ruta (University of Bucharest)24/09/2026, 17:00Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Saccharomyces cerevisiae is a valuable eukaryotic model for elucidating mechanisms of metal transport, accumulation, and homeostasis. In this study, we investigated the cellular response of yeast cells to oleandrin exposure, with particular emphasis on their capacity to accumulate heavy metals. Multi-elemental analysis revealed a selective and significant increase in intracellular Mnยฒโบ levels...
Go to contribution page -
Lavinia Ruta (University of Bucharest)24/09/2026, 17:05Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
The interplay between polyphenolic antioxidants and metal homeostasis is a complex and increasingly relevant topic with significant implications for biotechnology and environmental applications. While polyphenols are widely recognised for their antioxidant and metal-chelating properties, their role in modulating intracellular metal accumulation remains insufficiently explored.
Go to contribution page
In this study,... -
Prof. Narimantas ฤฤnas24/09/2026, 17:10Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
The phenolic phytocannabinoids frequently exhibit a prooxidant activity, however, its role in their toxic/therapeutic action remains unclear. Typically, the prooxidant character of mammalian cell cytotoxicity of hydroxybenzenes is demonstrated by a negative dependence of the cytotoxicity on the redox potential of phenoxyl radical/phenol couple (E(Ph-Oโข/Ph-OH) or E27 at pH 7.0). Here using...
Go to contribution page -
Mihaela Nedelkovska24/09/2026, 17:15Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
The production and consumption of gluten-free food products have significantly increased due to the global rise in celiac disease and non-celiac gluten sensitivity. Ensuring the safety of these products remains a critical challenge, as accidental cross-contamination can occur during manufacturing, storage, or transport.
Go to contribution page
While conventional detection relies heavily on immunochemical methods... -
Martina ล rajer Gajdoลกik (Josip Juraj Strossmayer University of Osijek - Department of Chemistry)24/09/2026, 17:20Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Nitrogen-containing heterocyclic compounds based on the imidazole scaffold are frequently utilized in crop protection and medicinal chemistry due to their exceptional capacity to interact with diverse biological targets.1 In the field of agrochemicals, compounds disrupting the cholinergic nervous system through the inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE)...
Go to contribution page -
Marija Paureviฤ (Josip Juraj Strossmayer University of Osijek - Department of Chemistry)24/09/2026, 17:25Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Imidazole derivatives are important heterocyclic pharmacophores in medicinal chemistry, well known for their broad spectrum of biological activities and therapeutic potential.1 In agricultural applications they target cholinesterases (acetylcholinesterase, AChE and butyrylcholinesterase, BuChE), which are important for the normal function of the nervous system in humans, other vertebrates and...
Go to contribution page -
Andrea Dandiฤ (University of Osijek, Department of chemistry)24/09/2026, 17:30Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Imidazole derivatives are well known for their broad spectrum of biological activities and significant applications in medicinal and agrochemical research, including anticancer, antifungal, antibacterial, anti-inflammatory, and neuroprotective effects.1 In addition to their medicinal importance, acetylcholinesterase (AChE) inhibitors are widely used as active ingredients in insecticidal plant...
Go to contribution page -
Mrs Milena Spasovska Kolevska (Institute of Chemistry, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University, Skopje)24/09/2026, 17:50Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Monocarbonyl analogs of curcumin (MACs) containing ฮฑ,ฮฒ-unsaturated carbonyl systems are electrophilic compounds capable of interacting with thiol-containing nucleophiles via thia-Michael addition.1,2 Their reactivity toward biologically relevant thiols, such as N-acetylcysteine, is important for understanding their chemical behavior and potential biological activity. In this study, we...
Go to contribution page -
Milena Spasovska Kolevska (Institute of Chemistry, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University, Skopje)24/09/2026, 17:55Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Monocarbonyl analogs of curcumin have attracted attention due to their diverse biological activity. They contain a cross-conjugated ฮฑ,ฮฒ-unsaturated enone system. The cyclic derivatives possess two exocyclic C=C bonds, conjugated with the central carbonyl group, and they are well-suited to act as Michael acceptors for biologically relevant thiols. One of the key lead compounds is EF24, or...
Go to contribution page -
Mr Arjan Ganiji (Institute of Chemistry, Faculty of Natural Sciences and Mathematics, Ss. Cyril and Methodius University, Arhimedova 5, 1000 Skopje, R. N. Macedonia; Faculty of Technology Science, Mother Theresa University, Mirce Acev 4, 1000 Skopje, R. N. Macedonia)24/09/2026, 18:00Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Although curcumin (CUR) has significant beneficial effects and biological activity, its clinical applications are limited due to its poor bioavailability, low absorption, rapid metabolism and low chemical stability. One approach to enhance the bioavailability of CUR is through the structural modification of its molecule. C5-curcuminoids (C5-CUR) that lack a ฮฒ-diketone moiety in their...
Go to contribution page -
Maja Sencheva Petrevska (Institute of Organic Technology, Faculty of Technology and Metallurgy, Ss. Cyril and Methodius University in Skopje, Skopje, North Macedonia)24/09/2026, 18:05Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
This study presents a two-step in silico strategy for the rational design of flavanone derivatives with improved antioxidant activity and favorable pharmacokinetic properties.1 Experimental vitamin C equivalent antioxidant capacity (VCEAC) data for flavanones were used to develop QSAR models based on ChemSketch descriptors. The models showed excellent statistical performance, with Rยฒ values...
Go to contribution page -
Dr Rusudan Kakava (Tbilisi State University)24/09/2026, 18:10Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
Chiral sulfoxides are valuable motifs in organic synthesis, medicinal chemistry, and pharmaceutical research. The present study addresses a central methodological challenge in biochirality research: how to control, monitor, and analytically resolve stereochemical outcomes in small chiral molecules. A series of aryl sulfides bearing electron-donating and electron-withdrawing substituents at...
Go to contribution page -
Viktorija Bezhovska (Alkaloid AD Skopje, Blvd. Aleksandar Makedonski 12, 1000 Skopje, Republic of North Macedonia)24/09/2026, 18:15Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
The critical quality attributes of the drug product and the efficiency of the manufacturing process for production of granules for oral suspension be affected by the the drying process. The impact of three different drying technologies singleโpot vacuum, fluid bed, and tray drying on granules produced by wet granulation was evaluated. An immediateโrelease formulation containing a BCS class IV...
Go to contribution page -
Ivana Atanasova (Quality Control Pharmaceuticals, ALKALOID AD Skopje)24/09/2026, 18:20Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
The determination of sulphated ash is a compendial analytical method, as prescribed in the European Pharmacopoeia, for the quantification of inorganic impurities in pharmaceutical and chemical substances. This study describes the configuration and validation of a sulphated ash calculation method using the LabX laboratory software system.
Go to contribution page
The method enables automated data capture and... -
Elena Stankovska (Alkaloid AD Skopje)24/09/2026, 18:25Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
ABSTRACT
Go to contribution page
In the pharmaceutical industry, ongoing stability monitoring of commercial batches is a mandatory requirement that often generates a large volume of samples and analytical tests, many of which provide redundant data for well-established products. This paper explores a quality risk management (QRM) approach, aligned with ICH Q1A (R2) and Q9 guidelines, aimed at streamlining ongoing... -
Mr Nikola Pavleski (Alkaloid AD)24/09/2026, 18:30Organic chemistry, biochemistry and pharmaceutical chemistryE-poster
The comparative evaluation between Bormed HE7541 PH and Purell ACP6541A as medical grade resins is important because both materials are widely used in Pharmaceutical packaging applications where mechanical performance, processability and regulatory compliance are critical. Bormedโข HE7541-PH is a bimodal high density polyethylene intended for evaluation for use in Healthcare applications and is...
Go to contribution page
Choose timezone
Your profile timezone: